- The following is taken from the "Celiac Sprue" handout flyer from CSA/USA: "...; personality changes
(especially common in children with sprue; they become unable to concentrate,
are irritable, cranky, and have difficulties with mental alertness and memory
function); can also occur in adults; ..."
- The following is from the February 1995
Sprue-nik Press newsletter. It included Misc. Highlights
from the 1994 American Celiac Society Conference.
"Question (to Alessio Fasano, Pediatric Gastroenterologist, University of
Maryland): Is there an association between celiac disease and attention
deficit or hyperactivity in children? Yes, but only for untreated celiacs.
Once the child goes on a gluten-free diet, these problems tend to disappear.
A related question: Is there a link between behavioral problems and celiac
disease in children? Once again, the answer is yes, but only for untreated
celiacs. It is the malnutrition that leads to the problem."
- From Gluten Intolerance Group
of North America - "Gluten-Sensitive Enteropathy: Up-Date for Health Care
Professionals" May, 1992: "Behavioral changes - such as irritability and
inability to concentrate, may be reported in undiagnosed children. Adults
often relate difficulties in short-term memory and concentration...."
- From Coeliac Disease, by Dr. Michael Marsh, Blackwell Scientific
Publications, November 1992. - Chapter 2 (by Jacques Schmitz) - p.30 - "The
effects of the gluten-free diet are most often spectacular, particularly in
toddlers. Behavioural disorders are the first to subside..."
- Marsh's book again - Chapter 3 - on CD in adults, written by Peter
Howdle and Monty S. Losowsky. p. 55 - "Psychological changes have also been
widely investigated, but are difficult to quantify. Many patients appear to
be depressed, while others are irritable, morose or difficult to relate
to... Nevertheless, in some case reports, treatment with a gluten-free diet
has resulted in spectacular improvements in mental function."
- From a speech by Ivor D. Hill, MD. Professor of Pediatrics, Duke
University entitled "Clinical Presentation of Celiac Disease in Children"
given on July 14, 1995:
Behavioral Disturbance: Emotional symptoms are common in children with
celiac disease, although they are not often the initial mode of presentation
of this condition. Children with celiac disease have been described as
"extremely irritable, fretful, capricious or peevish. Nothing seems to
please them and although they are quite unlike themself". They often exhibit
features of extreme emotional dependence on their mothers, frequently
clinging to them and showing marked irritability and fretfulness when
separated. In addition, they are often emotionally withdrawn from their
environment, and this withdrawal may even resemble autism. The association
between celiac disease and autism is still a matter of considerable debate
in some circles.
- Kalle Reichelt, M.D. of the Pediatric Research Institute in Oslo,
Norway has been researching the impact of gluten and casein intolerance
on certain individuals with developmental delays for many year. See his Collected Net Articles.
They are very enlightening, somewhat technical and include many
references to published studies. The articles include: food intolerances,
diet, mental disease, autism, schizophrenia, celiac disease, intestinal
permeability, milk protein, ADHD, downs syndrome, soy intolerances, and
more. An 80K page.
- Paul Shattock at the U. of Sunderland in the UK has a page on
The Use of Gluten and Casein Free Diets with People with Autism.
Also a paper on
Back to The Future: An assessment of some of the unorthodox forms of
biomedical intervention currently being applied to autism.
- Dr. Robert J. Cade of the University of Florida has been studying "exorphins" in the genesis and treatment of autism and schizophrenia. See letter and attachment that he at one time sent out to parents that contacted him. This dates from before his study was finished. In the attachment is some background and the early results of their study.
- autism-diet.com is Dr.
J. Robert Cade MD's site. Covers research, diet, people and resources. [now in archive.org]
- Univeristy of
Maryland Researchers Discover "Key" to Blood-Brain Barrier is a press
release on the identification of a receptor in the human brain that regulates
the interface between the bloodstream and the brain.
- From the top proponent of increased intestinal permeability: Leaky
Gut Syndromes: Breaking the Vicious Cycle by Leo Galland, M.D.
- John Coleman's Opioids In Common Food Products-Addictive
Peptides In Meat, Dairy and Grains is an easier read than the Reichelt
page, from which much of it is based. You will see that there is no evidence
for John to also include meat, except that as a vegan he also avoids it.
- The
origins of agriculture – a biological perspective and a new
hypothesis by Greg Wadley and Angus Martin argues that the shift to
cultivation and animal domestication was due to the "comfort" derived
from the opioid peptides from gluten.
- SerenAid is a digestive aid in case gluten is accidentally eaten. I wouldn't recommend it. But click on Gluten Free Diets to see their overview of diet and disorders of the autism spectrum.
- Sue Bennett at Your Autism Coach
is selling SerenAid and a booklet to help
the parents of young children who have just been diagnosed to help them
quickly put together a comprehensive and effective intervention program.
- Kirkman Laboratories sells scientific nutrition for autism and PDD. They carry products like Super Nu-Thera®, DMG, MSM, and others.
- The Good News Doctor, a.k.a. Jeff Bradstreet, M.D., has a page discussing biological treatments of autism. See various abstracts.
- Antibody Assay Laboratory in Santa Ana, CA had Urinary
Polypeptides testing available in the US for research use for $90. To find the page you have to select from the combo box at the top of the page.
The test must be authorized by a doctor. This test was developed with
the help of Paul Shattock. It is useful for: autism, ADD, ADHD, dyslexia
and obsessive compulsive disorder. Also see Intestinal Permeability
Evaluation which is on "Casein and Gliadin Antibodies: A novel
way to detect intestinal permeability".
- Sage Systems has a Comprehensive ELISA Allergy Test and Treatment for the Relief of Chronic Illness. See their page on Autism and its relationship to delayed food allergies.
- The Great Plains Laboratory
for Health, Nutrition, and Metabolism is Dr. William Shaw's site. They
specialize in urine organic acid testing. Much information is at this new
site. Another site: The
Great Plains Laboratory.
- Alletess Medical
Laboratory is the lab used by Dr. Cade. His study participants get the
"gluten and casein screen" test done, which looks for anti-gliaden and
anti-casein antibodies.
- Great Smokies Diagnostic Laboratory has a page on What is Functional
Medicine? which describes laboratory tests that allow practitioners to
understand a patient's functional status.
- BodyBio has tests for Blood Chemistry and Fatty Acid. BodyBio believes in using nutrition on functions and disorders. Included in each BioCell™ Report are: what foods to seek, foods to avoid, medication intolerances, vitamins needed, vitamins not needed, imbalances in major body organs.
- The former medical director of Immuno Labs now has his own business at Dr. Braly's Allergy Relief, the Natural Way. Test kits from York Nutritional Laboratories are used. See FoodSCAN which does not require a blood draw.
- The largest outfit that does ELISA testing for food allergy/intolerance is in Fort Lauderdale. The parent company site Immuno Laboratories is oriented towards doctors. Then they have a consumer site: Better Health USA Food Allergy Relief Center.
- And for those in the UK: York Nutritional Laboratory.
- The Autism Network
for Dietary Intervention (ANDI) sells several books: Lisa Lewis:
Special Diets for special kids.. Karyn Seroussi: Your gluten and
dairy free kitchen. William Shaw: The biological basis of autism and
PDD.
- Sue Dengate has
written two books: Fed Up - Understanding how food affects your child
and what you can do about it, and Different Kids - Growing up with
Attention Deficit Disorder. Her site has information about the effects of
food on children's behaviour, health and learning ability; and support for
families using the low chemical elimination diet: free of additives, low in
salicylates, amines and flavour enhancers.
- Brain Allergies: The Psychonutrient and Magnetic Connections details the science and theory behind Dr. Philpott's approach. Covers the impact our diets can have on the mental/emotional aspect of our lives.
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